Question about diflucan?

[gothstar.livejournal.com]

Ok this may be stupid but I'm on the nuvaring and got perscribed diflucan (actually its generic fluconazole) to clear up a yeastie beastie.

Ok, on my package the pharmacy slapped on a sticker that says "some medicines may decrease the effictivenes of birthcontrol pills"

I checked the drug interaction checker and it says that it may make side effects worse or something... this is what it says:

Azole antifungal agents may increase the plasma concentrations and, consequently, the pharmacologic effects of estrogens and progestins. The mechanism is decreased clearance of the hormones due to inhibition of CYP450 3A4 activity by azole antifungals. Fluconazole doses of 150 mg and 200 mg have been shown to increase the serum concentrations of ethinyl estradiol and levonorgestrel in healthy women receiving low-dose oral contraceptives, while single and multiple doses of fluconazole 50 mg had no significant effect on the pharmacokinetics of a high-dose oral contraceptive containing 150 mcg ethinyl estradiol and norgestrel 300 mcg. Ironically, there have been isolated reports of breakthrough bleeding and unintended pregnancy during use of oral contraceptives with itraconazole, which would suggest decreased rather than increased effect of the contraceptives. However, the association to itraconazole is questionable.


So they're saying that it actually increases the plasma concentrations which is not bad, but then it goes on to say that some people may have had BTB or unintended pregnancy...

Also, it says low-dose ORAL contraceptives, should I be less worried because I'm on the nuvaring?

I'm worried!!!! I hate using condoms (which I will of course if needed) but... what is your take on this oh great VPers!!!


EDIT: From the NuvaRing perscribing info

A single-dose vaginal administration of an oil-based 1200 mg miconazole nitrate capsule increased the
serum concentrations of etonogestrel and ethinyl estradiol by approximately 17% and 16%, respectively.
Following multiple doses of 200 mg miconazole nitrate by vaginal suppository or vaginal cream, the mean
serum concentrations of etonogestrel and ethinyl estradiol increased by up to 40%.


So it's saying suppositorally, the concentrations were upped, which doesn't mean that it gave out more hormones right? It jsut means... what exactly does that mean?

But that still isn't explaining what will happen if taken orally..

and then it says:

Contraceptive effectiveness may be reduced when hormonal contraceptives are co-administered with
some antifungals, anticonvulsants, and other drugs that increase metabolism of contraceptive steroids. This could result in unintended pregnancy or breakthrough bleeding. Examples include barbiturates,griseofulvin, rifampin, phenylbutazone, phenytoin, carbamazepine, felbamate, oxcarbazepine,
topiramate, and modafinil. Women may need to use an additional contraceptive method when taking
such medications.




I am just so confused...

spermicide, yeasties, contraception, etc.

[heartgut.livejournal.com]

Hey vag-fans, I have a few things I wanted to air out:

The other day I had my first meeting with a psychiatrist and we were going over this checklist of questions when the issue of sexual activity came up. I've been happily, exclusively gettin' it on with boyfriend... but that wasn't the issue. She asked me what we used for birth control (I'd mentioned earlier a bit about being on HBC previously and stopping because of gallbladder problems). When I told her we used condoms she explained that using a spermicide in addition would make it nearly or as effective as HBC. "Condoms are only 50, 60% effective, they have a high failure rate." But not THAT high... that's more like the failure rate of the withdrawel method. I didn't correct her, but explained that I avoid spermicides because I get yeast infections from using them and then things were utterly awkward for a few seconds.


Anyway, I'd figure I'd shoot for some feedback here on my contraceptive decisions as this conversation made me reeeally wish I had a second form of birth-control.

- HBC... freaks me out because a) I've personally had terrible reactions to 2 different brands, one causing swelling and "heaviness in the legs", etc, and the other ... well, my gallbladder, and b) I really am not convinced it's healthy at all to subject one's body to synthetic hormones.
- Spermicides... well, I'm only familiar with the long chemically nonoxil-something-word 9, which in the spermicidal/lubed condom form has never ceased to cause me some awful yeasties. Are there other, friendlier varieties?
- IUDs... hear it's not something for people who've been exposed to HPV.
What else is there? Diaphrams still involve spermicides, which my yeastly tendancies make me wary of...

Am I forgetting anything? Anything I seem to be misunderstanding?

Thanks!

tattoos during periods

[legu.livejournal.com]

I'm not sure if this is the right community to post this question, but is it generally a good idea to get a tattoo done during one's period? I'm not sure if there would be any adverse effects resulting from doing so (like too much stress on the body, etc).

Ejaculation! (Finally!)

[devora.livejournal.com]

I ejaculated during sex!!! This has never happened to me before with a partner. I can ejaculate during masturbation if there is a lot of G-spot stimulation, but for some reason I could never do it in front of a man. I think it's been mostly psychological. Fear of wetting the bed, or my partner not knowing that it's vaginal fluid, and thinking I pissed on him. But last night my boyfriend and I had sex, both came, and then before my bf got soft he stayed inside of me and started pumping me again. He immediatly bounced back and got hard again and suddenly I felt the urge come on. I had to focus. I had to relax and not fight it. Then suddenly it happened. My bf was very excited and pleased. So was I.

Burning when peeing

[bonkuraazu.livejournal.com]

First thing that comes to mind is a UTI right? I really don't think so because the burning usually occurs in the morning. After I pee a few times after during the day, the pain's gone. There's no urgency to pee either. It's just a burning sensation up my urethra when peeing in the morning.

It's not a yeast infection either I'm sure, there's no abnormal discharge or weird smells.

I've been sexually active (with one partner) for a year or so now, and we use condoms. I keep myself pretty clean down there wiping appropriately etc. Any idea on what might be the cause?

Vaginal art

[evilpinkbear.livejournal.com]

( apparently not work safe )

crossposted.

Sorry I'm not sure if this is slightly unrelated, but i wanted to get some advice from some women.

[greencloud06.livejournal.com]

I was wondering about anal sex. Is it possible for it not to be painful for the girl? Are there any girls that like it?
And also about cleanliness, hygene etc... Does anyone have any gross encounters? I mean sorry for being crude, but woldnt there be a slight amount of.. residue? On the condom I mean... THanks for any help!

[[sorry cross-posted]]

Bad PMS

[tamah-sama.livejournal.com]

So, when I PMS I don't get bitchy or moody or...you know, irritable really.

I get really depressed, really quiet, and I tend to get dangerously suicidal thoughts. Along with my period comes lethargy where I can hardly get out of bed, and for a good week I'm constantly fighting back urges to do stupid things.

Now I know that part of it is underlying problems, I do struggle with depression. And I'm pretty sure that part of this is anemia (which I take iron supplements for)

However, I still get like this every month, and I was wondering if going on BC would do anything?

azo yeast pills

[simplybasics.livejournal.com]

hi
i was taking azo yeast pills to treat, help out, whatever you may call it, my yeast infection, and they seemed to be helping, but suddenly they just stopped working.

can anyone explain why?
the clumpy discharge and serious itching went away months ago but i am still plagued by being very dry and am occasionally itchy. the azo helped the dryness.

i am so very confused..

help
please?