oh the data - do a pubmed such you'll see all kinds of data out there - is it conclusive? not at all! There is no multi times reproduced good data which points to it helping or hurting long term in females w/no issues such as IR, Type2, other risk factors such as obesity, HTN, hyperlipidemia etc - which is the issue. Not every female with PCOS has IR or Type 2 - however most will go on to develop it. Met is not without it's own risk and the way (IMHO/E) some medics throw it around is just not safe. There are a number of blood tests to be done before it is rx'ed, it has to be put though a "work up" phase, bloods re-tested and possibly have the med readjusted.
I will say this - It is well known that women with PCOS that are not IR or T2 that are having having issues getting pregnant/staying pregnant often will be given a mix of Met and Clomid - but even for this "common" practice there is no good data to tell us how the Met works etc and it is not done long term.
Also - there is no data to indicate that Met helps prevent IR or Type 2 which is one of the main concerns of women/medics when it comes to PCOS.
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Date: 2011-10-13 05:37 pm (UTC)There is no multi times reproduced good data which points to it helping or hurting long term in females w/no issues such as IR, Type2, other risk factors such as obesity, HTN, hyperlipidemia etc - which is the issue. Not every female with PCOS has IR or Type 2 - however most will go on to develop it.
Met is not without it's own risk and the way (IMHO/E) some medics throw it around is just not safe. There are a number of blood tests to be done before it is rx'ed, it has to be put though a "work up" phase, bloods re-tested and possibly have the med readjusted.
I will say this - It is well known that women with PCOS that are not IR or T2 that are having having issues getting pregnant/staying pregnant often will be given a mix of Met and Clomid - but even for this "common" practice there is no good data to tell us how the Met works etc and it is not done long term.
Also - there is no data to indicate that Met helps prevent IR or Type 2 which is one of the main concerns of women/medics when it comes to PCOS.